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It is also important to understand that because of the complicated nature of the effects of these treatments, they should only be used under the care of a medical professional with appropriate expertise and experience

It is important to note that AE1plays an important role in the maintenance of the structural integrity of erythrocytes, providing interactions between the membrane and the cytoskeleton, supporting the cytoskeletal connectivity, and maintaining the biconcave shape of erythrocytes [92]